Reimbursement Update for High-Cost Clinician-Administered Drugs (HCCADs)

Aug 19, 2025 | Provider Resource

Inpatient high-cost clinician-administered drugs (HCCADs) are drugs or biologics that the Texas Health and Human Services Commission (HHSC) has approved to be “carved out” of the All-Patient Refined Diagnosis Related Group (APR-DRG) and can be billed on an outpatient claim.

The section below contains the list of HCCADs, and procedure codes approved by HHSC:

Revised HCCADsRevised Procedure CodesEffective Date
AbecmaQ20556/2/2025
AucatzylQ20587/1/2025
BreyanziQ20546/2/2025
CarvyktiQ20566/2/2025
CasgevyJ33926/2/2025
ElevidysJ14136/2/2025
HemgenixJ14116/2/2025
KymriahQ20426/2/2025
LenmeldyJ33917/1/2025
LyfgeniaJ33946/2/2025
RoctavianJ14126/2/2025
SkysonaJ35906/2/2025
TecartusQ20536/2/2025
TecelraQ20576/2/2025
YescartaQ20416/2/2025
ZolgensmaJ33996/2/2025
ZyntegloJ33936/2/2025

Reimbursement Policy Update

Hospitals must submit claims for these HCCADs separately as outpatient claims on a UB04. These drugs will no longer be reimbursed under the All-Patient Refined Diagnosis Related Group (APR-DRG) payment system. Instead, reimbursement will be made as direct payments based on the lesser of:

  1. The Texas Medicaid Fee-For-Service (FFS) rate, or
  2. The actual acquisition cost, as documented by an invoice.

Billing Requirements

To ensure proper reimbursement, hospitals must:

  • Submit a separate outpatient claim on a UB04 for the HCCAD, separate from any institutional/facility claim for other hospital services provided on the same date.
  • Include the following details in the claim:
    • NDC Qualifier: N4
    • 11-digit National Drug Code (NDC) and corresponding HCPCS code
    • Number of units administered
    • NDC unit of measurement (F2, GR, ML, UN, or ME)
  • Use the date of drug administration as the date of service on the claim.
  • Submit an invoice reflecting the actual acquisition cost of the drug.

Note: Drugs administered during an inpatient setting do not qualify for 340B.

Action:

Providers are encouraged to share this information with their staff. If you have any questions about this notice, please email Provider Relations at ProviderRelations@cfhp.com or call 210-358-6030. You can also contact your Provider Relations Representative directly.

To access all Provider alerts:



Home
Member Portal
Provider Portal